Biorez

The Future of Tendon and Ligament Healing

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Introducing the BioBrace™ Implant

We pioneered the BioBrace™ implant to empower clinicians and raise the standard of care for the treatment of ligament and tendon injuries. The BioBrace™ implant is an innovative biocomposite scaffold that is intended for the reinforcement of soft tissue where weakness exists.
The BioBrace is not yet FDA cleared for commercial sale or clinical use in the United States.

Reinforce

Its biomechanical profile enables load sharing to reinforce ligament and tendon repair throughout the healing process.

Regenerate

Through its proprietary open porous architecture and biocompatible materials, the BioBrace™ facilitates a rapid cellular infiltration to accelerate organized tissue regeneration.

Resorb

After the healing process is complete, the implant will fully resorb to restore the anatomy to its normal state.

An Innovation for ACL Reconstruction

Breakthrough Biocomposite Design

Breakthrough Biocomposite Scaffold

The proprietary biocomposite design of the BioBrace™ features a highly-porous collagen matrix, embedded with bioresorbable polymer microfilaments, to provide an open 3-D biologic scaffold with strength.

Re-engineering ACL Augmentation

Re-engineering ACL Augmentation

Using biocompatible and bioresorbable materials, the BioBrace™ is an entirely new approach to augment soft tissue. The durable implant is easy to handle and readily added to existing surgical technique.

Optimizing the healing process

Optimizing the healing process

The highly porous scaffold is designed to facilitate a more rapid cell integration and re-vascularization, to optimize the healing process.

In ACL reconstructive surgery tissue grafts are typically used to replace the ruptured ACL.

After the graft is implanted, the body repopulates new cells and blood vessels through the tissue graft to reconstitute a new ACL over time. Prolonged recovery following ACL reconstructive surgery remains a challenge for both the patient and surgeon. Biorez has designed and developed the BioBrace™ implant to help solve this problem.

reconstructive surgery

shortcomings of $7B Sports Medicine Market

The natural healing process for ligaments and tendons can be long and slow due to low cellular activity and low vascularity within connective tissues. As a result, rehabilitation and recovery are long, often incomplete, and risk of reinjury is high.

ACL

ACL

250,000 Surgeries


Up to 29% graft failure (1)

rotator cuff

Rotator Cuff

460,000 Surgeries


Up to 34% re-tear (2)

Achilles

Achilles

70,000 Surgeries


Up to 16% re-tear (3)

(1) Barrett, AM et al. Anterior cruciate ligament graft failure: a comparison of graft type based on age and Tegner activity level. Am J Sports Med. 2011 Oct;39(10):2194-8.
(2) Gerber C et al. The results of repair of massive tears of the rotator cuff. J Bone Joint Surg Am. 2000 Apr;82(4):505-15.
(3) Rettig AC et al. Potential risk of rerupture in primary Achilles tendon repair in athletes younger than 30 years of age. Am J Sports Med. 2005 Jan;33(1):119-23.

The ability to optimize this healing process and shorten rehabilitation time would be a significant advancement.


Who We Are

Biorez Inc. is a late development stage orthopedic implant company that has a simple vision: to help patients with debilitating tendon and ligament injuries return to their normal, pre-injury activity levels sooner and safer than the current standard of care.

We are an experienced team of entrepreneurs, engineers, surgeons, scientists, veterinarians, and medical device business professionals.

The company is headquartered in New Haven, CT.

Biorez HQ

470 James Street, #14
New Haven, CT
06513 USA

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